Washington, North Carolina
Jamestown, North Carolina
San Francisco, California
Madisonville, Kentucky
Los Angeles, California
Santa Cruz, California
Cincinnati, Ohio
Ann Arbor, Michigan
Multiple (Indicate locations in Job Description)
Maysville, Kentucky
Paducah, Kentucky
Posted: 04-Nov-22
Location: La Jolla, California
Salary: Open
Internal Number: 119910
UCSD Layoff from Career Appointment: Apply by 11/7/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 11/16/2022 Eligible Special Selection clients should contact their Disability Counselor for assistance.
Placement within the salary range is determined by internal equity, relevant qualifications, and collective bargaining agreements (when applicable).
DESCRIPTION
The Advanced Cell Therapy Laboratory (ACTL) offers expert assistance and hands-on services to investigators who require cGLP/cGMP systems and facilities. We aid in the transition from research and development to compliant and clinically-relevant manufacture of cell therapy products for IND-enabling studies or Phase I/II trials.We provide assistance with cell banking, process scale-up, product characterization, document writing, product stability assessment, and packaging.
Under general supervision, responsible for performing GMP (Good Manufacturing Practice) cell culture and the associated assays within a laboratory or clean room. Perform a broad range of laboratory activities in the support of cell therapy products under cGMP for use in pre-clinical & clinical studies. Undertakes translational research and development and validation studies of processes and equipment as required. Performs all associated CTL procedures that are required to ensure the daily operation of the CTL and to maintain CTL licensing and accreditation, as indicated. Responsible for participating in the quality management and accreditation process. Responsible for culturing T cells, NK cells, neuronal cells, stem cells, embryonic stem cells, and other cell types derived from donors.
MINIMUM QUALIFICATIONS
Bachelor's degree in a science related field of study and one (1) year of relevant experience or a combination of experience and education required.
Hands-on experience in a pharmaceutical, biotech, drug manufacturing, or academic environment is required, with knowledge of clean room practices being essential.
Experience with aseptic cell culture methods, including cryopreserving, thawing, and expanding cell lines, is required.
Strong computer skills using MS Word, Excel and email.
Experience using basic laboratory equipment; knowledge of safe laboratory procedures.
Ability to follow detailed instructions described in SOPs and batch records and to record data accurately and in a legible manner per cGMP requirements.
Demonstrated ability to work with a variety of individuals including faculty, clinicians, and staff and to work as a team member in a support position.
Willingness to work in environment where biological (including infectious agents and blood borne pathogens), chemical, and radiological hazards are present, to perform research on the human pluripotent stem cell, to work with viruses that are infectious to humans, including adeno-associated viruses, Sendai viruses, and lentiviral vectors which are derived from human immunodeficiency virus (HIV).
PREFERRED QUALIFICATIONS
- Experience and knowledge in iPSC cell culture techniques, including culturing and maintenance.
- Familiarity with the Miltenyi CliniMACs device, flow cytometry, and PCR techniques.
SPECIAL CONDITIONS
- Employment is subject to a criminal background check.
- Willingness to work in BioSafety Level II environment where biological (including infectious agents and blood borne pathogens) hazards are present.
Pay Transparency Act Full Salary Range: $61,262 - $76,212 Annually
The University of California, San Diego is required to provide a reasonable estimate of the compensation range for this role. This range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be offered a salary at or near the top of the range for a position. Salary offers are determined based on final candidate qualifications and experience. The full salary range for this position is defined as the Full Pay Range. The budgeted salary or hourly range that the University reasonably expects to pay for this position defined as the Expected Pay Scale. Placement within the Expected Pay Scale is determined by internal equity, relevant qualifications, and collective bargaining agreements (when applicable).